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Indian J Physiol Pharmacol ; 1977 Jul-Sep; 21(3): 195-8
Article in English | IMSEAR | ID: sea-107097

ABSTRACT

Intravenously administered oxytocin caused a dose-related fall in blood pressure of the rabbit. When oxytocin was administered in oestrogen-primed animals, the depressor response was converted to a pressor one "Oxytocin reversal". The "oxytocin reversal." was abolished after treatment with dihydroergotamine, hexamethonium or adrenalectomy. The "oxytocin reversal" did not appear in reserpinized animals.


Subject(s)
Adrenalectomy , Animals , Blood Pressure/drug effects , Dihydroergotamine/pharmacology , Estriol/analogs & derivatives , Estrogens/pharmacology , Female , Hexamethonium Compounds/pharmacology , Male , Oxytocin/pharmacology , Pancuronium/analogs & derivatives , Rabbits , Reserpine/pharmacology , Stimulation, Chemical
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